The SUR2A Monoclonal Antibody from MyBioSource.com is a Mouse Monoclonal antibody to ABCC9. This antibody recognizes Porcine antigen. The SUR2A Monoclonal Antibody has been validated for the following applications: Western Blot.
Description
Sulfonylurea receptors (SUR) are membrane proteins that are molecular targets of the sulfonylurea class of antidiabetic drugs whose mechanism of action is to promote insulin release from pancreatic beta cells. SUR proteins are subunits of the inward-rectifier potassium ion channels Kir6.x (6.1 and 6.2). The association of four Kir6.x and four SUR subunits form an ion conducting channel commonly referred to as the KATP channel. The primary function of the SUR is to sense intracellular levels of ATP and ADP and facilitate the opening or closing of its associated Kir6.x potassium channel, thus monitoring the energy balance within cells